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(Solution) - Signaling molecules interact with cells through speci c macromolecular receptors For

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Signaling molecules interact with cells through speci?c macromolecular receptors. For each of the four receptors identi?ed below, list all characteris-tics, by number, which accurately describe that receptor.
(a) An adrenergic receptor ________
(b) A steroid receptor ____________
(c) Te LDL receptor _____________
(d) Te insulin receptor ___________
(1) Located at the cell surface
(2) Associated with the protein clathrin
(3) Ligand binding stimulates the activity of phospholipase C
(4) A transmembrane protein
(5) A DNA-binding protein
(6) Located in the cell interior
(7) Receptor-ligand complex moves to the lysosome
(8) Receptor-ligand complex becomes concentrated in the nucleus
(9) Receptor activation can inhibit the synthesis of glycogen
(10) Te hormone-receptor complex activates speci?c gene transcription
(11) Internalization decreases the synthesis of cholesterol esters
(12) Action of this receptor diminishes the synthesis and activity of ?-hydroxy-?-methylglutaryl-CoA reductase (HMG-CoA reductase)
(13) This receptor activates its own synthesis
(14) Biological activity of this receptor involves interaction with guanine nucleotide-binding proteins
(15) This receptor has a protein kinase activity
(16) Not known to act through a second messenger


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